By Howard Maibach, Golara Honari

Applied Dermatotoxicology: scientific Aspects offers concise, systematic, and cutting-edge info at the toxicological results of drugs on epidermis, and up to date advances in dermal toxicity trying out.

This booklet particularly addresses the scientific shows borne out of publicity to various chemical substances. It starts off with an outline of pores and skin biology to supply toxicologists with a easy knowing of its anatomy and body structure. subsequent it offers various dermatotoxicological results, in addition on the poisonous brokers that reason them, with colour pictures to demonstrate those results.

Applied Dermatotoxicology: medical Aspects is a necessary reference for toxicologists in undefined, and for these doctors who come upon instances of dermal publicity to poisonous brokers.

  • A concise, but inclusive evaluation of results of chemical exposure
  • Includes history on simple epidermis biology
  • Provides important medical reference for toxicologists in non-clinical settings

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Fischer T, Rystedt I. Cobalt allergy in hard metal workers. Contact Dermatitis. 1983;9:115À121. 138. Hayakawa R, Kato Y, Sugiura M, et al. Friction melanosis. In: Chew A, Maibach H, eds. Irritant Dermatitis. Berlin: Springer-Verlag; 2006:31À35. 139. Siragusa M, Ferri R, Cavallari V, et al. Friction melanosis, friction amyloidosis, macular amyloidosis, towel melanosis: many names for the same clinical entity. Eur J Dermatol. 2001;11:545À548. 140. Wong CK, Lin CS. Friction amyloidosis. Int J Dermatol.

Dermatology. vol. 2. China: Elsevier; 2012:1467À1486. 3. Polefka TG, Meyer TA, Agin PP, Bianchini RJ. Effects of solar radiation on the skin. J Cosmet Dermatol. 2012;11(2):134À143. 4. Diffey BL, Kochevar IE. Basic principles of photobiology. In: Lim HW, Honigsmnn H, Hawk JLM, eds. Photodermatology. USA; 2007:15À27. 5. Wondrak GT, Jacobson MK, Jacobson EL. Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection. Photochem Photobiol Sci. 2006;5(2):215À237.

17. Joint Research Centre of The European Commission’s in-house science service. pdf. 14. 18. Basketter DA, York M, McFadden JP, Robinson MK. Determination of skin irritation potential in the human 4-h patch test. Contact Dermatitis. 2004;51(1):1À4. 19. Patil SM, Patrick E, Maibach HI. Animal, human, and in vitro test methods for predicting skin irritation. In: Marzulli FN, Maibach HI, eds. Dermatotoxicology Methods. Washington, DC, USA: CRC Press; 1998:89À114. 20. Jirova D, Basketter D, Liebsch M, et al.

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