By Clifford A. Hudis M.D., Larry Norton M.D., David J. Winchester, David P., M.D. Winchester

A part of the yank melanoma Society's acclaimed Atlas of scientific Oncology sequence, this quantity deals knowledgeable evaluation of breast melanoma. issues variety from epidemiology and genetics to prognosis, administration and reconstruction. Post-treatment care, in addition to male breast melanoma, can also be mentioned.

Key gains: - greater than three hundred colour illustrations, photos, and radiographs express tumors as they appear - Discusses the most recent thoughts, corresponding to image-directed biopsy and sentinel node biopsy - contains contributions from prime surgeons, radiation oncologists, scientific oncologists, and gynecologists - followed by way of a CD-ROM with the entire textual content and illustrations of the publication, in absolutely searchable PDF records - photos could be downloaded for lectures and displays viewers: scholars and practitioners in surgical procedure, oncology, and gynecology, radiation oncology

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Additional info for Breast Cancer: Atlas of Clinical Oncology

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114 Such effects are thought to be caused by the reduction of plasma retinal levels, which occurs after administration of the retinoid. 97,111 The University of Texas M. D. 115 This phase II trial is accruing women presenting with small breast lesions and mammographic calcifications suspicious for malignancy. After histologic confirmation through core biopsies, participants are randomly assigned to receive tamoxifen, fenretinide, or a combination of both. The treatment is planned for 3 weeks before definitive surgery.

Placebo TAM vs. placebo 13,388 2,012 5,408 MD Anderson Cancer Center (USA)115 TAM +/-4-HPR (pre-operative) 4-HPR TAM vs. Raloxifene Study National Tumor Institute (ITALY) 94112 STAR (USA)94 Patient Population Ongoing High-risk, pre-/postmenopausal High-risk pre-/postmenopausal Post-hysterectomy No risk of breast cancer, pre-/postmenopausal Ductal carcinoma in situ 2,972 Ongoing History of breast cancer High-risk, pre-/postmenopausal BCPT = Breast Cancer Prevention Trial; NSABP = National Surgical Adjuvant Breast and Bowel Project; TAM = tamoxifen; 4-HPR = fenretinide (N-[4-hydroxyphenyl] retinamide, 4-HPR); STAR = Study of Tamoxifen and Raloxifene.

J Cell Biochem Suppl 1994;19:1–9. Grizzle WE, Myers RB, Arnold MM, Srivastava S. Evaluation of biomarkers in breast and prostate cancer. J Cell Biochem Suppl 1994;19:259–66. Fabian CJ, Kamel S, Zalles C, Kimler BF. Identification of a chemoprevention cohort from a population of women at high risk for breast cancer. J Cell Biochem 1996;25S:112–22. Gail MH, Brinton LA, Byar DP, et al. Projecting individualized probabilities of developing breast cancer for white females who are being examined annually.

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