By G.N. Kryzhanovsky

One infrequently continuously gets due credits for understanding a basic conception. it really is extra engaging to achieve success in researching new phenomena of actual evidence no matter if they're specific ones. the good technical possibilities which now exist and the hot equipment of research which lately tremendous have made that much more engaging. for this reason, the institution of basic regu­ larities looks an summary career whose value isn't regularly transparent. however, a normal concept might be elaborated. actual fabric may be systematized and generalized because it accumu­ lates. As an expanding volume of knowledge is got, it turns into more and more pressing to envision the final regularities which make sure the common mechanisms of person phenomena. Re­ searchers procedure those elements of clinical job in several methods. a few of them have an interest in interpreting the specifics of a phenomenon, whereas others attempt to discover a normal regularity in somebody truth and search for its affirmation in new fabric. either one of those vital types of examine were mirrored during this book.

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Extra resources for Central Nervous System Pathology: A New Approach

Sample text

This form of determination can be realized by preliminarily suppressing or directly changing the activity of the subordinated structures. An example of such effects is given in Figure 10. Under pathologic conditions, the complete dependence of the activity of the realizing structure is clearly exhibited in systems with rigid relationships in linearly organized nuclei. Hyperactive structures in such nuclei engender a syndrome whose peculiarities are determined by the way in which the structure functions.

The pattern of the activity of the system's parts that are subordinately influenced by the determinant only partially expresses the peculiarities of the determinant's functional transmission, and form III, or the activation of the system or its parts without imposing the pattern of the determinant's activity on them. Strictly speaking, the matter in question in the case of form III is not the determinant, but the generator of excitation which merely activates the system. The relations between such generators and the system which they activate have several distinguishing features.

Other indications are the same as in Figure 5. choline' activity in the focus, which is, for some reason, influenced more by the determinant focus (Figure 10 B 2). e. the potential generation frequency increases (Figure 10 B 3). At this stage, the determinant focus acts as a nonspecific activator with respect to the given focus: it does not impose its own mode of activity, but merely enhances the activity in that focus. Later, the specific components of the influence of the determinant focus become manifest: strychnine or penicillin potentials can be generated in the form of group dis- DETERMINANT STRUCTURES AS FUNCTIONAL FORMATIONS 19 charges whose duration corresponds to the acetylcholine discharge in the determinant focus.

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