By Dédée F. Murrell

This scientific case ebook serves as an invaluable consultant for dermatologists, internists, relatives practitioners, pediatricians, and a person else charged with the care of the outside. The case-based structure distinguishes this paintings from a reference-style textbook, as an alternative permitting readers to narrate the provided circumstances to their very own patients.

Clinical circumstances in Autoimmune Blistering ailments presents aid and perception for clinicians in handling this team of significant and debilitating pores and skin stipulations, with each one case serving as a springboard for extra pursuit and extra large education. it is going to permit these new to the sphere to start to strengthen a literacy and competence in autoimmune blistering ailments, whereas skilled dermatologists will locate new how one can sharpen their diagnostic and remedy skills.

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Br J Dermatol. 2012;166:154–60. 10. Martin LK, Werth V, Villanueva E, Segall J, Murrell DF. Interventions for pemphigus vulgaris and pemphigus foliaceus. Cochrane Database Syst Rev. 2009;1:CD006263. Chapter 6 A Crusted Plaque on the Right Cheek in a 45 Year Old Woman Maryam Ghiasi and Cheyda Chams-Davatchi A 45-year-old woman presented with a 6 × 4 cm crusted plaque surrounded by erythema on her right cheek with the involvement of lower eyelid since 1 month ago (Fig. 1). She had a history of generalized blisters and erosions especially on the face, scalp and upper trunk and painful erosions on the lip and oral mucosa from a few years ago that was treated with systemic corticosteroids.

After a few years, a 6 × 4 cm crusted plaque surrounded by erythema appeared on her right cheek with the involvement of lower eyelid. Intralesional triamcinolone was injected several times with the diagnosis of localized PV. The lesion had partial improvement but recurred at the same site a couple of times. Discussion PV is an autoimmune blistering disease with autoantibodies against the cell surface of keratinocyte. Initial involvement of oral mucosa is a well-known feature of the disease seen in 50–70 % of patients.

Key Pearls PV can sometimes require high doses of corticosteroids for prolonged periods to bring the disease under control. Careful monitoring for side effects of corticosteroid therapy should take place, and multi-disciplinary treatment may be warranted. Steroid-sparing drugs can help to reduce the exposure to systemic steroids. References 1. Gupta V, Kelbel T, Nguyen D, Melonakos K, Murrell D, Xie Y, et al. A globally available internet-based patient survey of pemphigus vulgaris: epidemiology and disease characteristics.

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