By H. Peter Soyer, giuseppe argenziano, Rainer Hofmann-Wellenhof, Robert H. Johr

As crucial a textual content for GPs as for dermatologists, this ebook is an atlas-like illustration of some of the varieties of melanocytic epidermis lesions linked to cutaneous melanomas and different pigmented pores and skin tumors. it's a entire and updated textual content at the useful concerns surrounding the administration of people with those lesions. It encompasses the classical tools of morphology comparable to the scientific and dermoscopic exam and dermatopathology. The booklet additionally bargains with the main up to date diagnostic techniques corresponding to laser scanning in-vivo microscopy and automatic prognosis. The visible ‘atlas’ comprises marvelous medical, dermoscopic and histopathologic photos.

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Extra resources for Color Atlas of Melanocytic Lesions of the Skin

Example text

6 Proliferations of Melanocytes at Sites of Inflammatory Skin Disorders. . . . . 4 Particular Histopathological Problems. . 1 Melanocytic Nevi with Several Cell Populations (“Combined” Nevi). . . . . 2 Nodular Proliferations of Melanocytes Within Congenital Nevi. . . . . . . . . 3 Superficial Proliferations of Melanocytes with Prominent Pigmentation. . . . . . 4 Proliferations of Melanocytes Associated with Prominent Inflammatory Response and/or Regression . . . .

The dermatopathological features, which at times may be mistaken for melanoma, most likely are caused by chronic irritation and/or repeated traumatic events. Diagnostic clues are the presence at the lateral edges of the lesion of conventional complexes of nevoid melanocytes, the restriction of the fibrotic changes to the center of it, and the absence of prominent pagetoid spread. These particular nevi are often located on the back of young adults. 6 Atypical Melanocytic Nevi with Degenerative Changes (“Ancient” Melanocytic Nevi) Ancient nevi have been described recently as benign histopathological simulators of melanoma [24, 48].

6. Congenital pseudomelanoma (proliferating nodules within congenital nevi in newborns). Note monomorphous population of large, atypical melanocytes melanocytes. Children presenting with such lesions, however, should be closely and carefully followed. 5. Melanocytic nevus biopsied shortly after birth. a Note complexes of a congenital melanocytic nevus in the dermis and prominent intraepidermal component. b Scatter of pleomorphic melanocytes within all layers of the epidermis lesions simulate a melanoma clinically as well as histopathologically, and are one of the most vexing problems in the realm of melanocytic lesions in newborns.

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