By Prasanti Babu, Anuj K. Chandel, Om V. Singh
Extremophiles are identified to thrive below harsh environmental stipulations. Many extremophilic bio-products are already used as life-saving medications. contemporary technological developments of structures biology have opened the door to discover those organisms anew as resources of goods that would turn out beneficial in scientific, environmental and drug development.
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Additional info for Extremophiles and Their Applications in Medical Processes
Nutrition 24:421–426 Grandy G, Medina M, Soria R et al (2010) Probiotics in the treatment of acute rotavirus diarrhoea. A randomized, double-blind, controlled trial using two different probiotic preparations in Bolivian children. BMC Infect Dis 10:253 Gudmundsdottir A, Palsdottir HM (2005) Atlantic cod trypsins: from basic research to practical applications. Mar Biotechnol 7:77–88 Guiliani N, Jerez CA (2000) Molecular cloning, sequencing, and expression of omp-40, the gene coding for the major outer membrane protein from the acidophilic bacterium Thiobacillus ferrooxidans.
1007/978-3-319-12808-5_4 37 38 4 Challenges in Advancing Extremophiles for Therapeutic … use extremophiles in therapeutic applications, various species must be studied in the extreme environmental conditions where they live. ) for scientists, however beneﬁcial the extremophiles may be (Mantelli 2003; Asker et al. 2011). Irwin and Baird (2004) reported that protein function and structure are important indicators of potential therapeutic applications. However, further research is needed to explore the properties and uses of the enzymes derived from the proteins and their corresponding extremophiles.
Am J Microbiol Res 2:94–104 Gabani P, Singh OV (2013) Radiation-resistant extremophiles and their potential in biotechnology and therapeutics. Appl Microbiol Biotechnol 97:993–1004 48 References Garcia-Descalzo L, Alcazar A, Baquero F et al (2013) Biotechnological applications of coldadapted bacteria. In: Singh OV (ed) Extremophiles—Sustainable resources and biotechnological implications. Wiley, Hoboken, pp 159–174 Georlette D, Damien B, Blaise V et al (2003) Structural and functional adaptations to extreme temperatures in psychrophilic, mesophilic and thermophilic DNA ligases.
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