By Reg R. Pascoe AM DVSc FRCVS FACVSc, Derek C. Knottenbelt OBE BVM&S DVM&S Dip ECEIM MRCVS

A concise guide of equine dermatology, totally illustrated in colour and diagnostically orientated. every one bankruptcy covers medical indicators, differential analysis and remedy, and emphasis is put on tips on how to distinguish comparable stipulations. the writer are world-renowned experts on equine dermatology.

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No evidence to support specific follow-up interval. AAD Task force recommends q3–12 months ϫ 2 years, then q6–12 months. (Sober et al. AAD Guidelines: Care for primary cutaneous melanoma. ) ***Evaluation: Strong evidence that routine CXR and blood work have limited value in patients with Stage 0/IA disease (Sober et al. AAD Guidelines: Care for primary cutaneous melanoma. ) CT, PET, MRI may be performed to evaluate specific sxs. Yes FNA or bx of ϩLN, then LND WLE Stage III Clinical ϩ nodes, macromet SLN* Margin (cm) Breslow depth (mm) G E N E R A L D E R M ATO L O G Y 39 DNA Human papilloma virus HHV1: HSV1 HHV2: HSV2 HHV3: VZV HHV4: EBV HHV5: CMV HHV6: Roseola infantum, reactivation increases drug-induced hypersensitivity syndrome severity HHV7: ?

1999; 40(4):507–35. 0 mm a: no ulceration and Clarks level II/III b: ϩ ulceration or Clarks level IV/V a: no ulceration b: ϩ ulceration a: no ulceration b: ϩ ulceration a: no ulceration b: ϩ ulceration N classification Nx N0 N1 N2 N3 Nodes cannot be assessed No regional lymphadenopathy 1 node a: micrometastasis b: macrometastasis 2–3 nodes a: micrometastasis b: macrometastasis c: satellite or in transit metastasis without metastatic nodes ജ4 nodes or matted nodes, or in transit mets/satellites and metastatic nodes Micrometastases: patients without clinical or radiologic evidence of LN mets (clinically occult) but with pathologically ϩ nodal mets after sentinel or elective lymphadenectomy Macrometastases: patients with clinically detectable of nodal metastases confirmed by therapeutic lymphadenectomy or when nodal mets exhibit gross extracapsular extension Adapted from Balch CM et al.

Ketron-Goodmann – disseminated pagetoid reticulosis, aggressive Granulomatous Slack Skin – pendulous atrophic lax skin, esp. axillae and groin. Associated with MF or Hodgkin lymphoma in 1/3 of cases. Usually indolent, very rare. Sezary – 5% of MF cases, triad of exfoliative erythoderma, lymphadenopathy, and atypical circulating (“Sezary,” ”Lutzner,” or “mycosis”) cells. MF-like immunophenotype but characteristically CD26and CD3ϩ but diminished. Change from Th1 to Th2 profile may drive progression to Sezary.

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