By John Y. M. Koo, Ethan C. Levin, Argentina Leon, Jashin J. Wu, Mark G. Lebwohl
A spouse to treatment of Moderate-to-Severe Psoriasis, moment variation, this reference deals professional information at the administration of psoriasis with chapters protecting contemporary advances together treatment, topical corticosteroids, calcipotriene, and phototherapy. delivering a realistic method of the various sorts of psoriasis, together with those who are relatively tricky to treat-including palmar-plantar, scalp, inverse, and nail psoriasis-this resource will function a must have software for each clinician taking good care of sufferers with those stipulations.
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Additional info for Mild-to-Moderate Psoriasis
Early clinical trials with topical steroids lasted only about one month during which time a good therapeutic response was obtained leading to the approval of these drugs. Subsequent experience and few studies suggest a loss of efﬁcacy over the next several months (17). If discontinued, topical steroids will have some effectiveness several months later. 2. Calcipotriene Cream, solution, and ointment preparations used twice a day (BID). Slow effectiveness, approximately two months for best effect.
Topical Agents for Psoriasis 39 12. Carlin CS, Feldman SR, Krueger JG, Menter A, Krueger GG. A 50% reduction in the psoriasis area and severity index (PASI 50) is a clinically signiﬁcant endpoint in the assessment of psoriasis. J Am Acad Dermatol 2004; 50:859–866. 13. Koo J, Kochavi G, Kwan JC. Topical medications for psoriasis. In: Kwan JC, ed. Contemporary diagnosis and management of psoriasis. 1st ed. , 2004:18–38. 14. Koo J, Kochavi G, Kwan JC. Determining disease severity. In: Kwan JC, ed.
Active medications to the scalp are often applied at night and shampooed out in the morning with standard hair preparations and conditioners as desired. Patients should be instructed in the quantity of topical medications applied to the skin. Basically, one should be rubbing in a thin ﬁlm to the skin without leaving a thick or visible coating on the surface. That is wasteful and expensive since the excessive medication will be rubbed off by the clothes. , corticosteroid, applied to the skin actually penetrates into the skin.
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