By Barbara H. Iglewski
The studies during this quantity care for questions of the mechanisms of pathogenesis and with organisms that experience only in the near past been broadly studied at the molecular level.**The introductory part provides an summary of pathogenesis, emphasizing universal parts and genetic mechanisms of law and a evaluate at the inhabitants genetics of bacterial pathogenesis. the second one part offers with the law of synthesis of floor elements and their position within the colonization of the host and/or of the host immune platforms. The 3rd part covers the invasion and intracellular progress of facultative and obligate intracellular parasites. The final part is dedicated to reports of the function of bacterial poisonous items in pathogenesis.
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Additional info for Molecular Basis of Bacterial Pathogenesis
Bacteriol. (in press). Smith, Ν. , and Selander, R. , (1990). Recombination of phase 1 flagellin genes generates new serovars of Salmonella. J. Bacteriol. (submitted for publication). 36 ROBERT Κ. SELANDER A N D JAMES M. , and Svanborg Eden, C. (1987). Virulence factors of Escherichia coli in urinary isolates from pregnant women. J. Infect. Dis. 1 5 6 , 8 7 0 - 8 7 7 . Stull, T. , LePuma, J. , and Edlind, T. D. (1988). A broad-spectrum probe for molecular epidemiology of bacteria: Ribosomal RNA.
Kl E. , 1976). This observation is in contrast to the low carriage rates of the other encapsulated bacteria causing meningitis such as H. influenzae type b, meningococci, and pneumococci. , 1975). , 1975). The presence of the Kl antigen was not only related to invasive disease but also to the severity of the outcome. Thus, infants with meningitis due to Kl E. , 1974). , 1974). , 1984; Scheld, 1984). B . VIRULENCE OF THE POLYSIALIC ACID CAPSULE The Kl capsule of E. coli is the sine qua non of this organism's virulence.
Whittam, T. , Old, D. C , and Selander, R. K. (1990). Reference collection of strains of the Salmonella typhimurium complex from natural popula tions. J. Bacteriol. (submitted for publication). Brenner, D. J. (1983). Impact of modern taxonomy on clinical microbiology. ASM News 4 9 , 5 8 - 6 3 . Brenner, D. J. (1984). Family 1. Enterobacteriaceae Rahn 1937. In "Bergey's Manual of Systematic Bacteriology" (N. R. Krieg and J. G. ), Vol. 1, pp. 4 0 8 - 4 2 0 . Williams & Wilkins, Baltimore, Maryland.
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