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Photodynamic therapy for distal and lateral subungual toenail onychomycosis caused by Trichophyton rubrum: preliminary results of a singlecentre open trial. Acta Derm Venereol 2010; 90: 216–17. Vanden Bossche H, Ausma J, Bohets H, et al. , and Microsporum canis. Antimicrob Agents Chemother 2004; 48: 3272–8. Vural E, Winfield HL, Shingleton AW, Horn TD, Shafirstein G. The effects of laser irradiation on Trichophyton rubrum growth. Lasers Med Sci 2008; 23: 349–53. 5 Lichen planus Lichen planus (LP) is a relatively common inflammatory skin disease that lasts from months to years.

Wu IB, Schwartz RA. Herpetic whitlow. Cutis 2007; 79: 193–6. 8 Warts PATHOGEN Human papillomavirus (HPV) DNA virus 1, 2, 4, and 7 cause butchers’ warts. There are now more than 90 different known types of HPV. HPV associated with skin lesions are classified as cutaneous HPV, which are different from the genital HPV associated with gynecological lesions. The difference between cutaneous types and genital types of HPV is that the cutaneous types do not have the E5 open reading frame (except for a few cutaneous types) compared with the genital types.

D. 19 Terbinafine or itraconazole content. Since toenail onychomycosis is frequently associated with tinea pedis, it may be best to collect samples for mycology from the soles. The same rule applies to the palms of patients with fingernail onychomycosis. TREATMENT Systemic Treatment Griseofulvin is no longer used and Ketoconazole has produced severe cases of hepatotoxicity. Itraconazole is given as a 200 mg dose once daily for 3 months or as a pulse therapy with intermittent dosing of 200 mg twice daily for 1 week each month over a period of 2 months for fingernail and 3 months for toenail fungal infections.

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