By David T. Denhardt, Ann F. Chambers (auth.), Hans E. Kaiser, Aejaz Nasir (eds.)

The techniques of tumor metastasis, apoptosis and anti-tumor immune reaction are one of the most intricate but speedily advancing fields within the quarter of melanoma examine. This monograph offers a accomplished insurance of the new advances within the a variety of key thoughts in those basic elements of human melanoma. it'd be of specific curiosity to contributors of the melanoma learn neighborhood, particularly those people who are actively fascinated by the learn of uncomplicated and translational elements of human melanoma. particularly, this quantity contains actual topic studies by way of best specialists at the following facets:

  • Control of tumor cellphone motility
  • Role of tumor-cell adhesion and migration in organ-selective metastasis-formation
  • Tumor heterogeneity when it comes to invasion and metastasis and its medical implications
  • Tumor angiogenesis, angioprevention, anti-angiogenic treatments and response
  • Role of apoptosis within the improvement, development and remedy of cancer
  • Role of macrophages in tumor improvement and metastasis
  • Pathways of macrophage-mediated tumor progression
  • Abnormal edition of immune reaction opposed to cancer
  • Immunological features of Marek’s sickness virus (MDV)-induced lymphoma progression
  • A biodynamical version of human T-cell proliferative disorders
  • Current methodologies for characterization of tumor directed immune response.

Show description

Read or Download Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response PDF

Best cancer books

The Official Patient's Sourcebook on Adult Brain Tumors: A Revised and Updated Directory for the Internet Age

This e-book has been created for sufferers who've determined to make schooling and learn an essential component of the therapy procedure. even though it additionally offers info valuable to medical professionals, caregivers and different health and wellbeing pros, it tells sufferers the place and the way to appear for info protecting nearly all issues relating to grownup mind tumors (also Acoustic schwannoma; Astrocytoma; mind tumor metastatic; mind tumor fundamental; mind tumor secondary; mind tumors), from the necessities to the main complicated components of analysis.

Fighting Cancer with Knowledge and Hope: A Guide for Patients, Families, and Health Care Providers (Yale University Press Health & Wellness)

A person who's clinically determined with melanoma gets a daunting blow, and in lots of situations the analysis is followed by way of a bewildering array of remedy offerings. during this important e-book, Dr. Richard C. Frank deals convenience and support to melanoma sufferers, their households, and their caretakers. Dr. Frank empowers sufferers by way of unlocking the mysteries of the illness and explaining in undeniable language the how you can confront and strive against it.

Cancer and Pregnancy

Te ecu university of Oncology is thrilled to ber of woman former melanoma sufferers anticipated to work out that the school of its path on melanoma and feature a profitable being pregnant. being pregnant has succeeded—and in a remarkably one other team of people that merits brief time—in generating this drastically stimulat - our recognition are ladies who've survived a ing ebook.

Optimization of Human Cancer Radiotherapy

The mathematical types during this e-book are focused on numerous ways to the way within which the medical radiologic remedy of human neoplasms could be more suitable. those advancements include methods of providing radiation to the malignan­ cies so one can create enormous harm to tumor cells whereas sparing neighboring basic tissues.

Extra resources for Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response

Example text

Cancer Res 34:997–1004 Loftus JC, Liddington RC (1997) New insights into the integrinligand interaction. J Clin Invest 100 (Suppl 11):77–81 Lu Z, Jiang G, Blume-Jensen P, Hunter T (2001) Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Mol Cell Biol 21:4016–4031 Maghazachi AA (2000) Intracellular signaling events at the leading edge of migrating cells. IJBCB 32:931–943 Max R, Gerritsen RR, Nooijen PT, Goodman SL, Sutter A, Keilholz U, Ruiter DJ, De Waal RM (1997) Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas.

CRC, Boca Raton, FL, pp 205–215 Ding LD, Sunamura M, Kodama T, Yamauchi J, Duda DG, Shimamura H, Shibuya K, Takeda K, Matsuno S (2001) In vivo evaluation of the early events associated with liver metastases of circulating cancer cells. Br J Cancer 85:431–438 Dong JT, Suzuki H, Pin SS, Bova GS, Schalken JA, Isaacs WB, Barrett JC, Isaacs JT (1996) Down-regulation of the KAI1 metastases suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.

Cancer Metastasis Rev 3:1–24 Weiss L, Orr FW, Honn KV (1988) Interactions of cancer cells with the microvasculature during metastasis. FASEB J 2:12–21 Westermarck J, Kähäri VM (1999) Regulation of metalloproteinase expression in tumor invasion. FASEB J 13:781–792 Wolf K, Mazo I, Leung H, Engelke K, von Adrian UH, Deruygina EI, Strongin AY, Brockner EB, Friedl P (2003) Compensation mechanism of tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol 160:267–277 Yamada N, Chung YS, Takasuka S, Arimoto Y, Sawada T, Dohi T, Sowa M (1997) Increased sialyl LeA expression and fucosyltransferase activity with acquisition of a high metastatic capacity in a colon cancer cell line.

Download PDF sample

Rated 4.18 of 5 – based on 32 votes