By Dr. John Coia, Dr. Heather Cubie (auth.), Dr. John Coia, Dr. Heather Cubie (eds.)

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Extra resources for The Immunoassay Kit Directory: Volume 1: Part 3 December 1995

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Dengue virus, for example, may be associated with more than one of these syndromes and is the most important arboviral cause of death and disease in man. Most arbovirus infections are however asymptomatic. Diagnosis (a) Encephalitis viruses: For differential diagnosis, all relevant arboviruses causing a similar disease may be examined together. Thus, in a patient in the 643 USA, St Louis encephalitis (SLE), Western/Eastern equine encephalitis (W/EEE) and California encephalitis (CE) are all important viral causes of encephalitis, but with different seasonal and regional distribution.

WEE, EEE Encephalitis Sindbis; Ross River virus;Chikungunya Fever and arthropathy Flaviviridae Flavivirus St Louis encephalitis; Japanese encephalitis; Tick-bourne encephalitis Dengue fever; West Nile fever Dengue; Yellow fever Fever, rash and arthralgia Haemorrhagic fever Californian encephalitis virus Sandfly fever; Rift valley fever virus Crimean Congo haemorrhagic fever virus Encephalitis Fever, abdom. pain & leukopaenia Haemorrhagic fever Colorado tick fever Fever, photophobia & myalgia Bunyaviridae Bunyavirus Phelobvirus Nairovirus Reoviridae Orbivirus Major symptoms © Encephalitis KLUWER ACADEMIC PUBLISHERS 1995, ISSN 1381-5067 644 THE IMMUNOASSA Y KIT DIRECTORY, SERIES B, VOLUME 1, PART 3 (ENTERIC AND OTHER INFECTIONS) Manufacturer: PanBio Manufacturer: PanBio Cat.

Diagnosis is usually based on detection of specific IgM in serum or CSF, using ELISA or IFA. IgM antibody to dengue may last more than 3 months making interpretation more difficult in endemic areas. Cross-reaction with other f1aviviruses can be extensive. In suspected cases of Japanese encephalitis, IgM can be found in CSF in the acute phase only. Comments The most effective means of control of arbovirus disease is by control of the arthropod vectors and by immunisation. Some vaccines are available, most notably, formalin inactivated vaccine for Japanese B encephalitis virus and live attenuated vaccine against yellow fever virus which was developed more than 50 years ago and control of dengue using engineered live attenuated virus is envisaged.

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