By Jennifer A. Cafardi (auth.)

The handbook of Dermatology used to be built through Dr. Cafardi on the college of Alabama at Birmingham, division of Dermatology, and covers vast dermatological themes valuable for any dermatology resident treating sufferers. themes contain alopecia, drugs dosing and administration pearls, fungal problems, genodermatoses, differential diagnoses of varied pores and skin illnesses, administration of infections, surgical anatomy and information, HIV dermatology, pediatric dermatology, and epidermis melanoma administration and terminology. The practicality of this publication is exclusive and comprises key scientific information for citizens, making it crucial as a reference for speedy differential diagnoses, work-up tips, administration, and remedies.

This speedy reference deals a simpler method of dermatology, with drug names and dosing, and additional information on mycology/onychomycosis than the other guide out there. The guide of Dermatology is transportable, accomplished, simply available, and is predicated upon algorithms, tables, and pearls taught to dermatology clinical scholars, making it an important source in all collage clinical libraries around the nation.

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Dimensions/extent? ■ Tufting ■ Atrophy and telangiectasis ■ Pigment changes ■ Other skin changes – skin, nails, mucosa ■ Labs – CBC, AST/ALT/Alk phos, G6PD, Eye exam, BUN/Cr, Blood pressure ■ Cultures and sensitivities ■ Treatments/comments ■ Biopsy ■ Photographs References: (1) Sperling LC. An Atlas of Hair Pathology with Clinical Correlations. New York: Parthenon, 2003. (2) Sperling LC. Alopecias. In: Bolognia, Jorizzo, Rapini (eds). Dermatology, 2nd edition. Spain: Mosby Elsevier, 2008: 997–8.

Women who develop this in the perimenopausal and menopausal phases have contributing genetic and hormonal factors Male androgenetic alopecia partially related to dihydrotestosterone (DHT). Testosterone converted to DHT by 5a-reductase. Type II 5a-reductase dominates in scalp, beard and chest hair, as well as in liver and prostate. Genetic absence of Type II 5a-reductase prevents male androgenetic alopecia Clinical Presentation Affects roughly 50% of men and perhaps as many women older than 40 years.

All headdresses have to be cleaned with antiseptic diligently and the patient should switch between hairpieces Oral antibiotics ○ Relapse is common after stopping ABX; patients often on low-dose ABX for years ○ Rifampin 300 mg BID over 10–12 weeks is believed to be the best antistaphylococcal agent. 5% triclosan cleanser; can be drying, so use in conjunction with antibiotic ointment Topical and Intralesional corticosteroids ○ Can help with the itching, burning, and pain ○ IL Kenalog 10 m/mL q4–6 weeks ○ Topical class I or II corticosteroids can be used BID ○ Oral corticosteroids ○ Consider PO prednisone only for highly active and rapidly progressing cases ○ Aggressive regimen – Prednisolone 20 mg QD tapered over 3 weeks + isotretinoin 40 mg QD, which is reduced to maintenance of 30 mg QD + PO clindamycin 300 mg QD × 6 weeks Isotretinoin ○ Limited used in folliculitis decalvans (but works well in dissecting cellulitis) Dapsone ○ 50–100 mg PO daily alone or in combination with an antibiotic ○ Long-term tx with 25 mg daily may stabilize the disease Isolated reports – Oral zinc sulfate, oral L-tyrosine, laser epilation with Nd:YAG.

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