By James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, Richard King, William Oetting, Jean-Paul Ortonne

The main accomplished and built-in ebook on pigmentation

The Pigmentary procedure, moment version, gathers into one handy, all-inclusive quantity a wealth of knowledge concerning the technological know-how of pigmentation and all of the universal and infrequent scientific issues that have an effect on dermis colour. the 2 elements, body structure (science) and pathophysiology (clinical disorders), are complementary and annotated in order that these examining one half can simply consult with correct sections within the different. For the clinician attracted to universal or infrequent pigment issues or the foundations of training approximately such issues, this e-book offers a right away and whole source at the biologic bases for those issues. For the scientist learning the biology of melanocyte functionality, the booklet offers a listing of problems which are relating to simple organic capabilities of melanocytes.

New positive aspects of this moment variation include:

* thoroughly new part at the easy technological know-how of pigmentation - explaining the mixing of melanocyte services with different epidermal cells and with a number of organ platforms just like the immune system

* New chapters on pigmentary issues with regards to intestinal ailments, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with slender band UV

* All medical chapters contain the newest genetic findings and advances in therapy

* greater than four hundred colour pictures of almost all medical disorders

The booklet is perfect for all dermatologists and particularly these attracted to problems of pigmentation. it really is of specific use for pediatric dermatologists and clinical geneticists taking good care of sufferers with congenital and genetic pigmentary issues. This authoritative quantity will fill the distance for dermatology education courses that don't have neighborhood specialists on pigmentation. easy and beauty scientists learning pigmentation and melanocytes will locate the technological know-how and medical correlations very valuable in exhibiting human value and relevance to the result of their studies.Content:
Chapter 1 A historical past of the technological know-how of Pigmentation (pages 1–10): Sidney N. Klaus
Chapter 2 Comparative Anatomy and body structure of Pigment Cells in Nonmammalian Tissues (pages 11–59): Joseph T. Bagnara and Jiro Matsumoto
Chapter three normal Biology of Mammalian Pigmentation (pages 61–90): Walter C. Quevedo and Thomas J. Holstein
Chapter four Extracutaneous Melanocytes (pages 91–107): Raymond E. Boissy and Thomas J. Hornyak
Chapter five rules of Melanoblast Migration and Differentiation (pages 108–139): David M. Parichy, Mark V. Reedy and Carol A. Erickson
Chapter 6 Melanoblast improvement and linked problems (pages 140–154): Richard A. Spritz
Chapter 7 Biogenesis of Melanosomes (pages 155–170): Raymond E. Boissy, Marjan Huizing and William A. Gahl
Chapter eight Melanosome Trafficking and move (pages 171–180): Glynis A. Scott
Chapter nine Melanosome Processing in Keratinocytes (pages 181–190): H. Randolph Byers
Chapter 10 The legislation of Melanin Formation (pages 191–212): Vincent J. Hearing
Chapter eleven The Tyrosinase Gene kinfolk (pages 213–229): William S. Oetting and Vijayasaradhi Setaluri
Chapter 12 Molecular legislation of Melanin Formation: Melanosome Transporter Proteins (pages 230–241): Murray H. Brilliant
Chapter thirteen Transcriptional rules of Melanocyte functionality (pages 242–260): Kazuhisa Takeda and Shigeki Shibahara
Chapter 14 Enzymology of Melanin Formation (pages 261–281): Francisco Solano and Jose C. Garcia?Borron
Chapter 15 Chemistry of Melanins (pages 282–310): Shosuke Ito and Kazumasa Wakamatsu
Chapter sixteen The actual houses of Melanins (pages 311–341): Tadeusz Sarna and Harold A. Swartz
Chapter 17 Photobiology of Melanins (pages 342–353): Antony R. Young
Chapter 18 Toxicological elements of Melanin and Melanogenesis (pages 354–394): Edward J. Land, Christopher A. Ramsden and Patrick A. Riley
Chapter 19 law of Pigment kind Switching by way of Agouti, Melanocortin Signaling, Attractin, and Mahoganoid (pages 395–409): Gregory S. Barsh
Chapter 20 Human Pigmentation: Its law via Ultraviolet gentle and via Endocrine, Paracrine, and Autocrine elements (pages 410–420): Zalfa Abdel?Malek and Ana Luisa Kadekaro
Chapter 21 Paracrine Interactions of Melanocytes in Pigmentary issues (pages 421–444): Genji Imokawa
Chapter 22 development issue Receptors and sign Transduction Regulating the Proliferation and Differentiation of Melanocytes (pages 445–463): Ruth Halaban and Gisela Moellmann
Chapter 23 getting older and Senescence of Melanocytes (pages 464–471): Debdutta Bandyopadhyay and Estela E. Medrano
Chapter 24 The Genetics of cancer (pages 472–488): Vanessa C. Gray?Schopfer and Dorothy C. Bennett
Chapter 25 The reworked Phenotype of Melanocytes (pages 489–494): Dong Fang and Meenhard Herlyn
Chapter 26 A extra specified Lexicon for Pigmentation, Pigmentary issues, and “Chromatic” Abnormalities (pages 497–503): James J. Nordlund, Tania Cestari, Pearl Grimes, Henry Chan and Jean?Paul Ortonne
Chapter 27 the conventional colour of Human epidermis (pages 504–520): James J. Nordlund and Jean?Paul Ortonne
Chapter 28 Mechanisms That reason irregular epidermis colour (pages 521–537): Jean?Paul Ortonne and James J. Nordlund
Chapter 29 Genetic Hypomelanoses: issues characterised via Congenital White recognizing ? Piebaldism, Waardenburg Syndrome, and comparable Genetic issues of Melanocyte improvement ? medical facets (pages 539–550): Richard A. Spritz
Chapter 30 Genetic Hypomelanoses: got Depigmentation (pages 551–598): Jean L. Bolognia, James J. Nordlund, Jean?Paul Ortonne and that i. Caroline Le Poole
Chapter 31 Genetic Hypomelanoses: Generalized Hypopigmentation (pages 599–635): Richard A. King, William S. Oetting, Philippe Bahadoran, Jean?Paul Ortonne, Anne?Sophie Gadenne, James J. Nordlund, Marnie D. Titsch, Allan D. Mineroff, Jean L. Bolognia and Tanusin Ploysangam
Chapter 32 Genetic Hypomelanoses: Localized Hypopigmentation (pages 636–656): Wolfgang Kuster, Rudolf Happle, James J. Nordlund, Jean L. Bolognia, Stella D. Calobrisi and Pranav B. Sheth
Chapter 33 Genetic Hypomelanoses: problems characterised through Hypopigmentation of Hair (pages 657–663): Stan P. Hill, Rosemary Geary, James J. Nordlund, Peggy Tong and Pranav B. Sheth
Chapter 34 Metabolic, dietary, and Endocrine issues (pages 664–668): Peter S. Friedmann
Chapter 35 Chemical, Pharmacologic, and actual brokers inflicting Hypomelanoses (pages 669–685): Stefania Briganti, Monica Ottaviani, Mauro Picardo and Jean?Phillipe Lacour
Chapter 36 Infectious Hypomelanoses (pages 686–698): Jean?Philippe Lacour
Chapter 37 Inflammatory Hypomelanoses (pages 699–704): Jean?Philippe Lacour
Chapter 38 Hypomelanoses linked to Melanocytic Neoplasia (pages 705–724): Lieve Brochez, Barbara Boone and Jean?Marie Naeyaert
Chapter 39 Miscellaneous Hypomelanoses: Depigmentation (pages 725–744): Philippe Bahadoran, Wiete Westerhof, David Njoo and Henk E. Menke
Chapter forty Miscellaneous Hypomelanoses: Hypopigmentation (pages 745–753): Wiete Westerhof, David Njoo, Henk E. Menke and Germaine Relyveld
Chapter forty-one Miscellaneous Hypomelanoses: Extracutaneous lack of Pigmentation (pages 754–766): Wiete Westerhof, David Njoo and Henk E. Menke
Chapter forty two Hypochromia with out Hypomelanosis (pages 767–768): Jean?Philippe Lacour
Chapter forty three Genetic Epidermal Syndromes: problems characterised through Generalized Hyperpigmentation (pages 769–779): Sheila S. Galbraith, Nancy Burton Esterly, Eulalia Baselga, Beth A. Drolet, Susan Bayliss Mallory and Sharon A. Foley
Chapter forty four Genetic Epidermal Syndromes: issues characterised via Reticulated Hyperpigmentation (pages 780–808): Eulalia Baselga and Nancy Burton Esterly
Chapter forty five Genetic Epidermal Syndromes with Cafe?au?lait Macules (pages 809–823): Nancy Burton Esterly, Eulalia Baselga and Sheila S. Galbraith
Chapter forty six Genetic Epidermal Pigmentation With Lentigines (pages 824–872): Mary ok. Cullen
Chapter forty seven Genetic Epidermal Syndromes: Localized Hyperpigmentation (pages 873–883): Nancy Burton Esterly, Eulalia Baselga, Beth A. Drolet and Sheila S. Galbraith
Chapter forty eight Genetic Epidermal Syndromes: issues of getting older (pages 884–897): Nancy Burton Esterly, Eulalia Baselga, Peter M. H. Chan, Beth A. Drolet, Anita P. Sheth and Cindy L. Lamerson
Chapter forty nine Congenital Epidermal Hypermelanoses (pages 898–906): Susan Bayliss Mallory, Peggy L. Chern and Sharon A. Foley
Chapter 50 obtained Epidermal Hypermelanoses (pages 907–978): Philippe Bahadoran, Norman Levine, Cynthia Burk, M Protein, James J. Nordlund, Vlada Groysman, Scott Bangert, Charles S. Fulk, Randi Rubenzik, Kazunori Urabe, Juichiro Nakayama, Yoshiaki Hori, Cindy L. Lamerson and Debra L. Breneman
Chapter fifty one Hypermelanosis linked to Gastrointestinal problems (pages 979–1002): Eun Ji Kwon, Victoria P. Werth, James J. Nordlund, Joerg Albrecht, Nancy Burton Esterly, Eulalia Baselga and Beth A. Drolet
Chapter fifty two got and Congenital Dermal Hypermelanosis (pages 1003–1019): Sang Ju Lee, Seung?Kyung Hann and Sungbin Im
Chapter fifty three combined Epidermal and Dermal Hypermelanoses and Hyperchromias (pages 1020–1025): Sang Ju Lee, Seung?Kyung Hann and Sungbin Im
Chapter fifty four Drug?Induced or ?Related Pigmentation (pages 1026–1054): Peter A. Lio and Arthur J. Sober
Chapter fifty five The Melanocyte process of the Nail and its problems (pages 1055–1068): Robert Baran, Christophe Perrin, Luc Thomas and Ralph Braun
Chapter fifty six Pigmentary Abnormalities and Discolorations of the Mucous Membranes (pages 1069–1089): John C. Maize and John C. Maize
Chapter fifty seven universal Benign Neoplasms of Melanocytes (pages 1091–1147): Julie V. Schaffer and Jean L. Bolognia
Chapter fifty eight infrequent Benign Neoplasms of Melanocytes (pages 1148–1162): James J. Nordlund, Julie V. Schaffer and Jean L. Bolognia
Chapter fifty nine Topical remedy of Pigmentary issues (pages 1163–1174): Rebat M. Halder and James J. Nordlund
Chapter 60 Chemophototherapy of Pigmentary issues (pages 1175–1182): Rebat M. Halder and James J. Nordlund
Chapter sixty one UVB treatment for Pigmentary problems (pages 1183–1187): Thierry Passeron and Jean?Paul Ortonne
Chapter sixty two Sunscreens and Cosmetics (pages 1188–1190): James J. Nordlund and Rebat M. Halder
Chapter sixty three Surgical remedies of Pigmentary problems (pages 1191–1197): Rebat M. Halder and James J. Nordlund
Chapter sixty four Laser remedy of Pigmentary issues (pages 1198–1203): Rebat M. Halder and Lori M. Hobbs

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Additional info for The Pigmentary System: Physiology and Pathophysiology, Second Edition

Example text

They showed that the intense melanization corresponded directly to elevated blood levels of MSH as measured by radioimmunoassay (RIA) (Fig. 29). Definitive proof that latent undifferentiated melanoblasts are the source of new melanophores comes from an unpublished study described by Bagnara and Fernandez (1993) in which the pars intermedia of juvenile Xenopus were implanted into the lower unpigmented jaw of larvae (Fig. 30). Melanophores differentiated in an area concentric to the implant, implying that they were derived from latent melanoblasts.

Among the more common types found in amphibians and fishes are those represented by long, thin profiles (Fig. 12). Among the leaf frogs, small bead-like or cubic reflecting platelets prevail (Fig. 13) as they often do in some lizards (Fig. 14). , 1978b). 17. Fig. 12. An iridophore from the dorsum of an adult R. pipiens showing stacks of reflecting platelets (actually spaces previously occupied by purine crystals that shattered and dissolved during sectioning and staining). An individual reflecting platelet is trapped between two lobes of the nucleus.

494–495). [From Bagnara, J. , and M. E. Hadley. Chromatophores and Color Change: The Comparative Physiology of Animal Pigmentation. ] Fig. 4. Epidermal melanophores of adult Rana pipiens, dispersed at left and aggregated at right. Note cytocrine melanin in adjacent epidermal cells. Each epidermal melanocyte with its surrounding epidermal cells comprises an epidermal melanin unit (courtesy of Professor M. E. Hadley). 15 CHAPTER 2 V pre mel V mel pre Fig. 6. Dispersed (left) and aggregated (right) dermal melanophores in the tail fin of Xenopus larvae.

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